Pancreatic cancer: any prospects for prevention?
نویسنده
چکیده
Primary prevention of pancreatic cancer and public health measures to reduce its incidence are dependent on data from epidemiological studies. Currently, the only definite risk factor is smoking, although a diet rich in fruit and vegetables may be protective. The K-ras mutation may have a role in diagnosis and screening.
منابع مشابه
Chemoprevention of pancreatic cancer: ready for the clinic?
Advances in our molecular, clinical, and epidemiologic understanding of the risk and development of pancreatic cancer offer hope for preventing this disease, which is largely intractable once developed. This perspective on provocative, genetically engineered mouse model work reported by Mohammed et al. (beginning on page 1417 in this issue of the journal) examines the prospects for pancreatic c...
متن کاملmoprevention of Pancreatic Cancer: Ready for the Clinic?
nloaded ances in our molecular, clinical, and epidemiologic understanding of the risk and development of eatic cancer offer hope for preventing this disease, which is largely intractable once developed. This ctive on provocative, genetically engineered mouse model work reported by Mohammed et al. ning on page 1417 in this issue of the journal) examines the prospects for pancreatic cancer preven...
متن کاملAbsence of deleterious palladin mutations in patients with familial pancreatic cancer.
It has been reported that germline mutations in the palladin gene (PALLD) cause the familial aggregation of pancreatic cancer, but the evidence is weak and controversial. We sequenced the coding regions of PALLD in 48 individuals with familial pancreatic cancer. We did not find any deleterious mutations and find no evidence to implicate mutations in PALLD as a cause of familial pancreatic cancer.
متن کاملAssociation between alcohol consumption and pancreatic cancer: a systematic review of cohort studies
Background: Among all types of cancers, pancreatic cancer has poor prognosis with 5-year survival below 10%. In theory, alcohol intake may be a modifiable risk factor for pancreatic cancer due to its role in multiple carcinogenic and metabolic signaling pathways. In addition, alcohol consumption may lead to chronic pancreatitis which is underlying cause of pancreatic cancer. However, little is ...
متن کاملJewish ethnicity and pancreatic cancer mortality in a large U.S. cohort.
BACKGROUND An association between Jewish ethnicity and pancreatic cancer risk was suggested by analyses comparing pancreatic cancer mortality rates between Jews and non-Jews in New York in the 1950s. These analyses lacked information on potential confounding factors and the association between Jewish ethnicity and pancreatic cancer has not been examined in any contemporary U.S. population or in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Postgraduate medical journal
دوره 75 887 شماره
صفحات -
تاریخ انتشار 1999